Consolidating new memories requires the amygdala and

24-Sep-2019 03:20 by 7 Comments

Consolidating new memories requires the amygdala and

It refers specifically to all that you remember as well as your capacity for remembering. Some memories are meant to be retained for a short period and then discarded.For example, you remember the telephone number of the local pizza place only long enough to make the call.

While psychologists and neuroscientists debate the exact role of the hippocampus, they generally agree that it plays an essential role in both the formation of new memories about experienced events and declarative memory (which handles facts and knowledge rather than motor skills).The process of learning new information, storing it, and recalling it involves a complex interplay of brain functions (see Figure 1).Researchers and neuroscientists have devised several classification systems to describe the various forms of memory.One major system relies on duration, making a distinction between short-term memories, which are fleeting, and long-term memories, which can persist for a lifetime.Another scheme breaks memories down according to the type of information they contain, such as whether they are straight facts, specific events, or learned procedures for doing something.Memory consolidation involves synaptic and broad cellular events that include transcriptional, translational, and post-translational mechanisms, as well as their feedback and feedforward regulation.

These molecular changes start with the initial encoding and evolve with time because memory consolidation seems to occur in stages (Alberini, 2008, 2009; Dudai, 1996, 2012; Mc Gaugh, 2000; Squire & Alvarez, 1995).Memory consolidation is a category of processes that stabilize a memory trace after its initial acquisition.Like encoding, consolidation affects how well a memory will be remembered after it is stored: if it is encoded and consolidated well, the memory will be easily retrieved in full detail, but if encoding or consolidation is neglected, the memory will not be retrieved or may not be accurate.The conclusion drawn from these studies indicated that consolidation is an evolutionarily conserved process of memory formation that requires an initial phase of RNA and protein synthesis [].The classical view proposes that memory consolidation is a unitary process through which a newly formed memory, which is initially sensitive to disruption, becomes stable over time; once stabilized, the memory remains insensitive to disruption.The findings that stabilized memories can become labile have challenged the classical view of how memories are consolidated over time and stored.

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